snai2 sirna (Santa Cruz Biotechnology)
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93
Structured Review
Santa Cruz Biotechnology
snai2 sirna
Snai2 Sirna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/slug+sirna/SLUG+siRNA/pmc10587525-37-0-3
Average 93 stars, based on 24 article reviews
Snai2 Sirna, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 24 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/slug+sirna/SLUG+siRNA/pmc10587525-37-0-3
Average 93 stars, based on 24 article reviews
snai2 sirna - by Bioz Stars,
2026-09
93/100 stars
Images
1) Product Images from "MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor"
Article Title: MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor
Journal: iScience
doi: 10.1016/j.isci.2023.108131
Figure Legend Snippet: SNAI1 and SNAI2 inhibited miR-92b expression (A) The expression of miR-92b-3p in HK2 cells treated with TGF-β for 12 h, as detected by qPCR, n = 5. (B) Sequence logo of transcription factor SNAI1 and SNAI2. (C–E) Protein levels of SNAI1, SNAI2, and β-actin in HK2 cells treated with SNAI1 siRNA (siSNAI1), SNAI2 siRNA (siSNAI2), or control siRNA as indicated in the figure, as detected by western blotting; quantitative results are shown; n = 3. Expression of Col1a1 and miR-92b-3p as determined by qPCR; n = 5. (F) Schematic representation of the human THBS3-AS1 promoters with the putative E2-box promoter shown as a red box. (G) A series of truncated THBS3-AS1 promoters fused to the luciferase reporter gene was co-transfected into HEK293T cells under TGF-β stimulation together with the pcDNA3.1 Renilla plasmid (Ctrl). The relative luciferase activity was presented as folds of Ctrl (n = 3). (H) DNA fragments containing the flanking region of the E2-box on the THBS3-AS1 promoters were immunoprecipitated with anti-SNAI1 or anti-SNAI2 antibodies. Data are expressed as means ± SD; n = 6 per group; ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001. Similar results from three independent experiments are shown.
Techniques Used: Expressing, Sequencing, Control, Western Blot, Luciferase, Transfection, Plasmid Preparation, Activity Assay, Immunoprecipitation
Figure Legend Snippet:
Techniques Used: Recombinant, Control, Plasmid Preparation, Software, Modification, Staining, Extraction, Bicinchoninic Acid Protein Assay, Western Blot, cDNA Synthesis, SYBR Green Assay, Immunohistochemistry, Isolation
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